SNP – Communicable Diseases Research

Bioinformatics pipeline unveils genetic variability to synthetic vaccine design for Indian SARS-CoV-2 genomes

Article

Published on 2022-11-012022-11-15
Journal: International immunopharmacology
[Category] SARS, 치료기술, 치료제,

Evidence of co-infections during Delta and Omicron SARS-CoV-2 variants co-circulation through prospective screening and sequencing

Article

Published on 2022-11-012022-11-15
Journal: Clinical microbiology and infection : the official
[Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제,

[키워드] analysis chimeric circulation Co-infection collected COVID-19 Delta Delta and Omicron VOC Epidemic epidemiologically evidence of France generate Genetic Health Infection K417N L452R Mutation nasopharyngeal sample omicron Pandemics pathogenic patients PCR assay polymorphism primer sets profile Recombination recombination event Respiratory samples S-gene mutation Sample SARS-CoV-2 SARS-CoV-2 co-infection SARS-CoV-2 genome SARS-CoV-2 variant screened sequence Sequencing single nucleotide Single nucleotide polymorphism Single nucleotide polymorphism screening SNP SNPs submitted Surveillance variant virus VoC was performed WGS whole genome Whole genome sequencing whole genome sequencing.
[DOI] 10.1016/j.cmi.2022.06.030 PMC 바로가기

A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants

Article

Published on 2022-10-062022-11-16
Journal: Cell Stem Cell
[Category] COVID19(2023년), SARS, 변종,

COVID-19 infection and transmission includes complex sequence diversity

Article

Published on 2022-09-082022-11-15
Journal: PLoS Genetics
[Category] SARS, 변종, 진단,

Inflammasome Genetic Variants Are Associated with Protection to Clinical Severity of COVID-19 among Patients from Rio de Janeiro, Brazil

Article

Published on 2022-09-052022-11-16
Journal: BioMed Research International
[Category] SARS, 변종, 유전자 메커니즘,

[키워드] activated allele association Asymptomatic Brazil CARD8 center clinical clinical evolution Clinical management clinical manifestations contributing to COVID-19 COVID-19 severity death disease disease severity Factors Genetic Genetic variant Genotype group Haplotype Host host cells Inflammasome Inpatient investigated knowledge logistic regression models mechanism moderate NLRP3 NLRP3 inflammasome outcomes Patient performed polymorphism Polymorphisms profile protection Real-time PCR recruited Rio de Janeiro risk risk factor SARS-COV-2 infection SARS-CoV-2-infected individual scale severe symptom severity Significant single-nucleotide SNP SNPs Symptom the WHO two group two groups variants virus was determined WHO with mild disease
[DOI] 10.1155/2022/9082455 PMC 바로가기

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll-like receptors dictates pathophysiology of COVID-19 disease

주로 전염증성 사이토카인, 사이토카인 수용체 및 톨 유사 수용체의 개별 유전적 다양성이 COVID-19 질병의 병태생리를 좌우합니다

Review

Published on 2022-09-012022-09-11
Journal: Journal of medical virology
[Category] COVID19(2023년), SARS, 변종,

[키워드] acquired immunity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Alter B cells chemokine chemokines Clinical outcome clinical outcomes coding gene coding genes condition coronavirus coronavirus disease Coronavirus disease-19 Coronavirus-2 COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 severity cytokine Cytokine storm Cytokines determine exacerbate Gene Expression genes encoding Genetic genetic variability Genetic variation Genetic variations Host IL10 IL17 IL4 IL6 IL7 immune immune response immune responses Immunity individual Infection Inflammation Innate interferons Monocytes Mutation natural killer cell Natural killer cells Neutrophils nucleotide pathophysiology Patient polymorphism proinflammatory cytokines receptors respiratory symptoms response SARS-COV-2 infection Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe respiratory symptoms severity of COVID-19 Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs susceptibility T cells the patient TLR TLR3 TLR7 TLR9 TLRs TNF Toll-like receptor Toll-like receptors Toll-like receptors. understanding variants of concern Variation viral infection viral infections VOCs
[DOI] 10.1002/jmv.27849 PMC 바로가기 [Article Type] Review

Single-Nanoparticle-Based Digital SERS Sensing Platform for the Accurate Quantitative Detection of SARS-CoV-2

Article

Published on 2022-08-312022-11-15
Journal: ACS applied materials & interfaces
[Category] SARS, 변종, 치료기술, 치료제,

Gene Variants Related to Cardiovascular and Pulmonary Diseases May Correlate with Severe Outcome of COVID-19

심혈관 및 폐 질환과 관련된 유전자 변이가 COVID-19의 심각한 결과와 관련될 수 있음

Article

Published on 2022-08-042022-09-11
Journal: International Journal of Molecular Sciences
[Category] 변종,

IFNAR2 relevance in the clinical outcome of individuals with severe COVID-19

중증 COVID-19 환자의 임상 결과에서 IFNAR2 관련성

Article

Published on 2022-07-292022-09-11
Journal: Frontiers in Immunology
[Category] 변종, 치료제,

[키워드] amplify Antiviral antiviral response assays association beta receptor Clinical outcome COVID-19 COVID-19 mortality cytokine Cytokines determined by ELISA evaluate Genetic genetic susceptibility Genetic variant genetic variants Hospitalized IFN IFNAR1 IFNAR2 IFNs immunomodulatory activities individual individuals Innate immunity interferon Interferon alpha interferon alpha-beta interferons investigated Mortality mortality risk Non-survivors Patient patients hospitalized plasma sample plasma samples Protein receptor receptors severe COVID-19 severe COVID-19. severity SNP subject subunit survivor the disease Type type I IFNs variant with COVID-19
[DOI] 10.3389/fimmu.2022.949413 PMC 바로가기 [Article Type] Article

Are Pain Polymorphisms Associated with the Risk and Phenotype of Post-COVID Pain in Previously Hospitalized COVID-19 Survivors?

이전에 입원한 COVID-19 생존자의 통증 다형성이 COVID-19 이후 통증의 위험 및 표현형과 관련이 있습니까?

Article

Published on 2022-07-262022-09-11
Journal: Genes
[Category] 변종,

[키워드] All participants Anxiety association BDNF carried clinical feature Clinical features cognitive collected COMT COVID-19 de novo depressive distribution distributions Features female Gender Genotype Hospitalization hospitalized COVID-19 HTR1B involved kinesiophobia long-COVID Musculoskeletal neuropathic neuropathic pain no differences no effect not significantly different nucleotide OPRM1 Pain participant Participants participated phenotypic feature phenotypic features polymerase chain reaction polymerase chain reactions polymorphism Post-COVID Psychological risk rs4680 rs6265 selected sensitization single nucleotide Single nucleotide polymorphism single nucleotide polymorphism. sleep quality SNP SNPs survivor Survivors Symptom Symptoms variable variant were assessed
[DOI] 10.3390/genes13081336 PMC 바로가기 [Article Type] Article